BDBM50254075 (R)-3-(3,4-dichlorophenyl)-N-methyl-3-(naphthalen-1-yl)propan-1-amine hydrochloride::CHEMBL460590

SMILES CNCC[C@H](c1ccc(Cl)c(Cl)c1)c1cccc2ccccc12

InChI Key InChIKey=BEJKUIRPKMIZPE-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254075   

TargetSodium-dependent serotonin transporter(Rat)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254075((R)-3-(3,4-dichlorophenyl)-N-methyl-3-(naphthalen-...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254075((R)-3-(3,4-dichlorophenyl)-N-methyl-3-(naphthalen-...)
Affinity DataIC50: 9.70nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254075((R)-3-(3,4-dichlorophenyl)-N-methyl-3-(naphthalen-...)
Affinity DataKi:  1.64E+3nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed