BDBM50254522 5-methyl-N,N-diphenyl-1-(2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-1H-pyrazole-3-carboxamide::CHEMBL517577

SMILES Cc1cc(nn1-c1ccccc1C(=O)N1CCc2ccccc2C1)C(=O)N(c1ccccc1)c1ccccc1

InChI Key InChIKey=GTQPMXUXXJDUHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254522   

TargetApoptosis regulator Bcl-2(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254522(5-methyl-N,N-diphenyl-1-(2-(1,2,3,4-tetrahydroisoq...)
Affinity DataIC50: 800nMAssay Description:Inhibition of GST fused Bcl-2 binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254522(5-methyl-N,N-diphenyl-1-(2-(1,2,3,4-tetrahydroisoq...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of GST fused Bcl-xL binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed