BDBM50254563 3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL461229

SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(cc21)C(N)=O

InChI Key InChIKey=NBEPKKBOGWVFFT-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254563   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50254563(3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50254563(3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]U69593 form kappa opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50254563(3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50254563(3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOpioid receptor delta 1(Cavia porcellus)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50254563(3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]Naltrindole from DOR in guinea pig brain membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed