BDBM50254563 3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL461229
SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(cc21)C(N)=O
InChI Key InChIKey=NBEPKKBOGWVFFT-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50254563
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]U69593 form kappa opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Displacement of [3H]Naltrindole from DOR in guinea pig brain membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair