BDBM50254651 CHEMBL516851::N-(2-(4-chlorophenyl)-2H-pyrazolo[3,4-c]quinolin-4-yl)isonicotinamide

SMILES Clc1ccc(cc1)-n1cc2c(n1)c(NC(=O)c1ccncc1)nc1ccccc21

InChI Key InChIKey=HEQDRFVPVBRJKB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254651   

TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254651(CHEMBL516851 | N-(2-(4-chlorophenyl)-2H-pyrazolo[3...)
Affinity DataKi:  24.7nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50254651(CHEMBL516851 | N-(2-(4-chlorophenyl)-2H-pyrazolo[3...)
Affinity DataIC50:  145nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as inhibition of CI-IB-MECA-mediated inhibition of cAMP accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed