BDBM50255036 (S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-3-(pyrimidin-4-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide::CHEMBL518422
SMILES O=C(Cn1c2ccccc2n(-c2ccncn2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31
InChI Key InChIKey=RIWBPOKEPFFMJB-NDEPHWFRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50255036
Affinity DataKi: 0.610nMAssay Description:Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...More data for this Ligand-Target Pair