BDBM50256012 (S)-2-cyclopentyl-2-(3-(3-mesitylureido)-2-naphthamido)acetic acid::CHEMBL513400

SMILES Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)N[C@@H](C2CCCC2)C(O)=O)c(C)c1

InChI Key InChIKey=PTLMRHVAGWFRJQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50256012   

TargetGlycogen phosphorylase, liver form(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256012((S)-2-cyclopentyl-2-(3-(3-mesitylureido)-2-naphtha...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human liver glycogen phosphorylase A by fluorescence intensity endpoint assay in presence of glucoseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256012((S)-2-cyclopentyl-2-(3-(3-mesitylureido)-2-naphtha...)
Affinity DataIC50: 321nMAssay Description:Inhibition of human liver glycogen phosphorylase A in HepG2 cells assessed as forskolin-induced glycogenolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256012((S)-2-cyclopentyl-2-(3-(3-mesitylureido)-2-naphtha...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed