BDBM50259862 13,II8-biapigenin::3,8''-biapigenin::CHEMBL515252::I3,II8-biapigenin::cid_10414856

SMILES O=c1c(-c2c(O)cc(O)c3c(=O)cc(-c4ccc(O)cc4)oc23)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12

InChI Key InChIKey=IQAMTZLKUHMPPE-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50259862   

TargetCytochrome P450 3A4(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259862BDBM50259862(cid_10414856 | 13,II8-biapigenin | CHEMBL515252 | ...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50259862BDBM50259862(cid_10414856 | 13,II8-biapigenin | CHEMBL515252 | ...)
Affinity DataIC50: 2.73E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetPC4 and SFRS1-interacting protein(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50259862BDBM50259862(cid_10414856 | 13,II8-biapigenin | CHEMBL515252 | ...)
Affinity DataIC50: 3.52E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2014
Entry Details
PCBioAssay
TargetPC4 and SFRS1-interacting protein(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50259862BDBM50259862(cid_10414856 | 13,II8-biapigenin | CHEMBL515252 | ...)
Affinity DataIC50: 4.23E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2014
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259862BDBM50259862(cid_10414856 | 13,II8-biapigenin | CHEMBL515252 | ...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259862BDBM50259862(cid_10414856 | 13,II8-biapigenin | CHEMBL515252 | ...)
Affinity DataKi:  4.60E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259862BDBM50259862(cid_10414856 | 13,II8-biapigenin | CHEMBL515252 | ...)
Affinity DataKi:  1.01E+4nMAssay Description:Binding affinity to human recombinant MIF extracted from Escherichia coli BL21 (DE3) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259862BDBM50259862(cid_10414856 | 13,II8-biapigenin | CHEMBL515252 | ...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human recombinant MIF extracted from Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed