BDBM50263376 CHEMBL476989::N-(2-chloro-6-methylphenyl)-1-(6-chloropyrimidin-4-yl)-1H-benzo[d]imidazol-2-amine

SMILES Cc1cccc(Cl)c1Nc1nc2ccccc2n1-c1cc(Cl)ncn1

InChI Key InChIKey=KWIZJTLRQLEMEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263376   

TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263376(N-(2-chloro-6-methylphenyl)-1-(6-chloropyrimidin-4...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Lck by lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263376(N-(2-chloro-6-methylphenyl)-1-(6-chloropyrimidin-4...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of TEL fused Lck-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed