BDBM50264813 (2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARBOXAMIDO)(PHENYL)PROPANOIC ACID::(R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophene-2-carboxamido)propanoic acid::CHEMBL508461

SMILES OC(=O)C[C@@H](NC(=O)c1cc(cs1)-c1ccc(cc1)-c1ccncc1)c1ccccc1

InChI Key InChIKey=VMTJQZUZINLEKC-JOCHJYFZSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50264813   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARB...)
Affinity DataIC50:  980nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARB...)
Affinity DataIC50:  14nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARB...)
Affinity DataIC50:  270nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARB...)
Affinity DataIC50:  390nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARB...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARB...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed