BDBM50265035 CHEMBL495729::N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-yl)-2-(pyrrolidin-1-yl)isonicotinamide

SMILES: Cc1nnc(o1)-c1ccc(c(C)c1)-c1cc(NC(=O)c2ccnc(c2)N2CCCC2)ccc1C

InChI Key: InChIKey=OBHNTFJGFUEQCQ-UHFFFAOYSA-N

Data: 1 KI  10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50265035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Sgk1 (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50265035 (N-(2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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