BDBM50265253 (S)-2-amino-3-(1H-indol-3-yl)-N-(2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethyl)propanamide::CHEMBL525917
SMILES N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCNc1c2CCCCc2nc2ccccc12
InChI Key InChIKey=IAWFZVSZFNIINF-NRFANRHFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50265253
TargetCholinesterase(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 1.33nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Rattus norvegicus)
University Of Hradec Kralove
Curated by ChEMBL
University Of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of nNOS in Wistar rat cortical homogenates incubated for 30 minsMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair