BDBM50266091 1-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea::1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea::CHEMBL468612

SMILES CNc1nccc(n1)-c1cccnc1Oc1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1C

InChI Key InChIKey=INFGJUQNPPGDNS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266091   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50266091(1-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50:  34nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50266091(1-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Tie2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed