BDBM50267661 CHEMBL608379

SMILES CC1(C)CC(NC(=S)Nc2ccc(cc2)[N+]([O-])=O)c2cc(Cl)ccc2O1

InChI Key InChIKey=VGYSEYVWIATBOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267661   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267661(CHEMBL608379)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267661(CHEMBL608379)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed