BDBM50268905 (2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-N-hydroxy-2-(3-phenylpyrrolidine-1-carbonyl)piperidine-3-carboxamide::CHEMBL495797

SMILES NCCCCCNC(=O)CC1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CCC(C1)c1ccccc1

InChI Key InChIKey=VXPAAABROXRBQT-XHXISMBCSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50268905   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268905((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268905((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268905((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50268905((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...)
Affinity DataIC50:  161nMAssay Description:Inhibition of human recombinant ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268905((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50268905((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...)
Affinity DataIC50:  162nMAssay Description:Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed