BDBM50269080 (S)-2,3-dimethyl-9-phenyl-6-(1H-1,2,4-triazol-1-yl)-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridine::CHEMBL498252

SMILES Cc1nc2c3N[C@@H](CCc3c(cn2c1C)-n1cncn1)c1ccccc1

InChI Key InChIKey=ZGALKRMWGKUOEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269080   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50269080((S)-2,3-dimethyl-9-phenyl-6-(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 700nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50269080((S)-2,3-dimethyl-9-phenyl-6-(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50269080((S)-2,3-dimethyl-9-phenyl-6-(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed