BDBM50269557 CHEMBL4069387

SMILES: CC(C)C(=O)N1CCC[C@H](C1)c1nc(-c2ccc(cc2F)C(=O)Nc2cc(ccn2)C(F)(F)F)c2c(N)nccn12

InChI Key: InChIKey=VTJHGMZHVOXJPG-UHFFFAOYSA-N

Data: 18 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50269557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Yes (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase TXK (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Blk (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	894	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Srms (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase FRK (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	472	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fgr (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 6 (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM50269557 (CHEMBL4069387) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	646	n/a	n/a	n/a	n/a	n/a	n/a
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