BDBM50273703 6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one::CHEMBL462093

SMILES O=C1CCc2cc(ccc2C1)-c1cccnc1

InChI Key InChIKey=XMIVJNDWTQQRAQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50273703   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273703(6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one | C...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273703(6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one | C...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273703(6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one | C...)
Affinity DataIC50: 3.96E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273703(6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one | C...)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273703(6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one | C...)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273703(6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one | C...)
Affinity DataIC50: 4.15E+4nMAssay Description:Inhibition of human recombinant CYP2C19 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273703(6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one | C...)
Affinity DataIC50: 1.71E+5nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed