BDBM50273704 5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one::CHEMBL448743

SMILES O=C1CCc2cc(ccc12)-c1cccnc1

InChI Key InChIKey=QNSOPUXDEXJMIY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50273704   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273704(5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one | CHEMBL...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273704(5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one | CHEMBL...)
Affinity DataIC50: 819nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273704(5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one | CHEMBL...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273704(5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one | CHEMBL...)
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273704(5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one | CHEMBL...)
Affinity DataIC50: 1.47E+5nMAssay Description:Inhibition of human recombinant CYP2C19 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed