BDBM50274918 (+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole::(-)-6-(3-benzylpyrrolidin-3-yl)-1H-indole::6-(3-benzylpyrrolidin-3-yl)-1H-indole::CHEMBL459165

SMILES C(c1ccccc1)C1(CCNC1)c1ccc2cc[nH]c2c1

InChI Key InChIKey=VHOZFHYPZOTVKS-UHFFFAOYSA-N

Data  8 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50274918   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataKi:  8nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataKi:  21nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataKi:  78nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataKi:  78nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataKi:  190nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataKi:  190nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataKi:  447nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataKi:  447nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataIC50:  900nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274918((+)-6-(3-benzylpyrrolidin-3-yl)-1H-indole | (-)-6-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed