BDBM50277509 3-(Cyclohexyloxy)-4'-(2-{[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino}ethyl)-N-(methylsulfonyl)biphenyl-4-carboxamide Dihydrochloride::CHEMBL445481

SMILES CS(=O)(=O)NC(=O)c1ccc(cc1OC1CCCCC1)-c1ccc(CCNC[C@H](O)c2cccnc2)cc1

InChI Key InChIKey=YLQMAAMFQNYJDU-MHZLTWQESA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50277509   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277509(3-(Cyclohexyloxy)-4'-(2-{[(2R)-2-hydroxy-2-pyridin...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277509(3-(Cyclohexyloxy)-4'-(2-{[(2R)-2-hydroxy-2-pyridin...)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277509(3-(Cyclohexyloxy)-4'-(2-{[(2R)-2-hydroxy-2-pyridin...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Canis familiaris)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277509(3-(Cyclohexyloxy)-4'-(2-{[(2R)-2-hydroxy-2-pyridin...)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed