BDBM50279045 (Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylicAcid Methyl Ester::CHEMBL525203

SMILES: COC(=O)c1ccc2C(C(=Nc3ccc(CN(C)C(=O)N(C)C)cc3)c3ccccc3)C(=O)Nc2c1

InChI Key: InChIKey=BQUCMYBIGNGMFC-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50279045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM50279045 ((Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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