BDBM50285612 CHEMBL4167599

SMILES NCCCCNCCCCNCCCn1c(=O)c2ccc3c4c(ccc(c24)c1=O)c(=O)n(CCCCCC(=O)NO)c3=O

InChI Key InChIKey=AKKLHGKRQKYMAM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50285612   

TargetHistone deacetylase 6(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50285612(CHEMBL4167599)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in baculovirus infected Sf21 insect cells using RHKKAc as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50285612(CHEMBL4167599)
Affinity DataIC50: 560nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Fluor de Lys as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50285612(CHEMBL4167599)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG-His tagged HDAC1 (1 to 482 residues) expressed in Sf21 insect cells using RHK-K(Ac)-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50285612(CHEMBL4167599)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant human C-terminal GST-tagged HDAC2 (1 to 488 residues) expressed in baculovirus infected Sf21 insect cells using RHK-K(Ac)-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50285612(CHEMBL4167599)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf21 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed