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BDBM50286270 CHEMBL100697::N-[(2-Dodecyl-2H-tetrazol-5-yl)-phenyl-methyl]-2,6-dimethyl-benzamide

SMILES: CCCCCCCCCCCCn1nnc(n1)C(NC(=O)c1c(C)cccc1C)c1ccccc1

InChI Key: InChIKey=IBUUHJHUWCNKGA-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286270   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)
BDBM50286270
PNG
(CHEMBL100697 | N-[(2-Dodecyl-2H-tetrazol-5-yl)-phe...)
Show SMILES CCCCCCCCCCCCn1nnc(n1)C(NC(=O)c1c(C)cccc1C)c1ccccc1
Show InChI InChI=1S/C29H41N5O/c1-4-5-6-7-8-9-10-11-12-16-22-34-32-28(31-33-34)27(25-20-14-13-15-21-25)30-29(35)26-23(2)18-17-19-24(26)3/h13-15,17-21,27H,4-12,16,22H2,1-3H3,(H,30,35)
PDB

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UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 110n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in intestinal microsomes isolated from chole...


Bioorg Med Chem Lett 5: 289-294 (1995)


Article DOI: 10.1016/0960-894X(95)00024-N
BindingDB Entry DOI: 10.7270/Q2FQ9WKP
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50286270
PNG
(CHEMBL100697 | N-[(2-Dodecyl-2H-tetrazol-5-yl)-phe...)
Show SMILES CCCCCCCCCCCCn1nnc(n1)C(NC(=O)c1c(C)cccc1C)c1ccccc1
Show InChI InChI=1S/C29H41N5O/c1-4-5-6-7-8-9-10-11-12-16-22-34-32-28(31-33-34)27(25-20-14-13-15-21-25)30-29(35)26-23(2)18-17-19-24(26)3/h13-15,17-21,27H,4-12,16,22H2,1-3H3,(H,30,35)
PDB

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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 310n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...


Bioorg Med Chem Lett 5: 289-294 (1995)


Article DOI: 10.1016/0960-894X(95)00024-N
BindingDB Entry DOI: 10.7270/Q2FQ9WKP
More data for this
Ligand-Target Pair