BDBM50292546 3,4,5,6-tetrahydroxyxanthone::CHEMBL477921::US9114126, MB7

SMILES Oc1ccc2c(oc3c(O)c(O)ccc3c2=O)c1O

InChI Key InChIKey=MUWSBAZQOGXKJK-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292546   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292546(3,4,5,6-tetrahydroxyxanthone | CHEMBL477921 | US91...)
Affinity DataKi:  1.26E+5nMAssay Description:Inhibition of ACE by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50292546(3,4,5,6-tetrahydroxyxanthone | CHEMBL477921 | US91...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of recombinant C-terminal 6xHis-tagged MTH1 (3 to 156 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
The University Of Toledo

US Patent
LigandPNGBDBM50292546(3,4,5,6-tetrahydroxyxanthone | CHEMBL477921 | US91...)
Affinity DataIC50:  5.00E+3nMpH: 7.4 T: 2°CAssay Description:The purified Na/K-ATPase was prepared from pig kidney. The specific activities of Na/K-ATPase of various kidney preparations were in the range of 900...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292546(3,4,5,6-tetrahydroxyxanthone | CHEMBL477921 | US91...)
Affinity DataIC50:  2.39E+5nMAssay Description:Inhibition of ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed