BDBM50294162 (R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen-3-yl)phenyl)methanone::CHEMBL561639::{4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone

SMILES O=C(c1ccc(OC[C@H]2CCCN2)cc1)c1ccc(cc1)-c1ccsc1

InChI Key InChIKey=VUWFJUJWAWMRQN-HXUWFJFHSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294162   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50294162((R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen...)
Affinity DataIC50:  81nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294162((R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen...)
Affinity DataIC50:  189nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair