BDBM50296636 4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-ylamino)benzamide::CHEMBL561932

SMILES: Cn1c2n(ncc2c(Nc2cc(ccc2Cl)C(=O)NC2CC2)cc1=O)-c1ccc(F)cc1

InChI Key: InChIKey=VPYHMFOFGLWNPN-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50296636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 13 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 12 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50296636 (4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
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