BDBM50300453 2,2-bis(2,3-dihydrobenzofuran-5-yl)-N-hydroxyacetamide::CHEMBL583967

SMILES ONC(=O)C(c1ccc2OCCc2c1)c1ccc2OCCc2c1

InChI Key InChIKey=WEOWFSNVPPFUOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300453   

TargetHistone deacetylase 5(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300453(2,2-bis(2,3-dihydrobenzofuran-5-yl)-N-hydroxyaceta...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC5 (620-1122) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300453(2,2-bis(2,3-dihydrobenzofuran-5-yl)-N-hydroxyaceta...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC7 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300453(2,2-bis(2,3-dihydrobenzofuran-5-yl)-N-hydroxyaceta...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed