BDBM50300472 5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid::CHEMBL583588

SMILES OC(CCc1ccc(cc1)-c1ccc(cc1)C#N)CC(O)=O

InChI Key InChIKey=YDAZWMGCTBJQEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300472   

TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300472(5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300472(5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300472(5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed