BDBM50302926 (1R,2R)-2-(tert-butylamino)-1-phenylpropan-1-ol::(1R,2S)-2-(tert-butylamino)-1-phenylpropan-1-ol::(1RS,2RS)-2-(N-tert-Butylamino)-1-phenyl-1-propanol::CHEMBL157455

SMILES CC(NC(C)(C)C)C(O)c1ccccc1

InChI Key InChIKey=USKJECUROJSHQU-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302926   

TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302926((1R,2S)-2-(tert-butylamino)-1-phenylpropan-1-ol | ...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302926((1R,2S)-2-(tert-butylamino)-1-phenylpropan-1-ol | ...)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [125I]RTI55 from cloned human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302926((1R,2S)-2-(tert-butylamino)-1-phenylpropan-1-ol | ...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302926((1R,2S)-2-(tert-butylamino)-1-phenylpropan-1-ol | ...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed