BDBM50303436 9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-9H-purine-2-carbonitrile::CHEMBL578159

SMILES: FC(F)Cn1cnc2c(Nc3cc(F)cc(F)c3)nc(nc12)C#N

InChI Key: InChIKey=VMJFQUMKCMNFSX-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50303436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cruzipain (Trypanosoma cruzi)	BDBM50303436 (9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin G (Human)	BDBM50303436 (9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.48E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Chymase (Human)	BDBM50303436 (9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neutrophil elastase (Human)	BDBM50303436 (9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Kallikrein-4 (Human)	BDBM50303436 (9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-1 (Human)	BDBM50303436 (9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 1 (Human)	BDBM50303436 (9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin Z (Human)	BDBM50303436 (9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-14 (Human)	BDBM50303436 (9-(2,2-difluoroethyl)-6-(3,5-difluorophenylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
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