BDBM50304588 (R,S)-N-[2-Benzoyl-4-(3-phenylpropionyl)aminophenyl]-2-(4-methylpiperazin-1-yl)-2-phenylacetamide::CHEMBL595713

SMILES CN1CCN(CC1)C(C(=O)Nc1ccc(NC(=O)CCc2ccccc2)cc1C(=O)c1ccccc1)c1ccccc1

InChI Key InChIKey=POMIGTJNLSPLAH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304588   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50304588((R,S)-N-[2-Benzoyl-4-(3-phenylpropionyl)aminopheny...)
Affinity DataEC50:  60nMAssay Description:Inhibition of ABCB1 overexpressed in human CCRF-CEM/VCR1000 cell assessed as inhibition of daunomycin efflux after 30 mins by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed