BDBM50305446 (R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-ureidobutyl)-N-((S)-1-cyclohexyl-3-(methylamino)propan-2-yl)piperidine-1-carboxamide::CHEMBL592048

SMILES CNC[C@H](CC1CCCCC1)NC(=O)N1CCC[C@H](C1)[C@@](O)(CCCNC(N)=O)c1cccc(Cl)c1

InChI Key InChIKey=XXQKRNVVWCJOMV-RWCIVJTCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305446   

TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305446((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-ureidobu...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305446((R)-3-((S)-1-(3-chlorophenyl)-1-hydroxy-4-ureidobu...)
Affinity DataIC50:  31nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed