BDBM50305466 CHEMBL592765::methyl 2-((R)-(3-chloro-5-fluorophenyl)((R)-1-((S)-1-cyclohexyl-3-(methylamino)propan-2-ylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate
SMILES CNC[C@H](CC1CCCCC1)NC(=O)N1CCC[C@H](C1)[C@@H](OCCNC(=O)OC)c1cc(F)cc(Cl)c1
InChI Key InChIKey=YSVOUYNGWGGLQG-DCEDVJGZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50305466
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair