BDBM50306256 1-(3-(pyrazin-2-yl)propanoyl)-2,3,9,9a-tetrahydro-1H-benzo[de][1,7]naphthyridin-7(8H)-one::CHEMBL609002

SMILES: O=C(CCc1cnccn1)N1CCc2cccc3C(=O)NCC1c23

InChI Key: InChIKey=GFHLWWHOLUWZLZ-UHFFFAOYSA-N

Data: 5 IC50  1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50306256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Human)	BDBM50306256 (1-(3-(pyrazin-2-yl)propanoyl)-2,3,9,9a-tetrahydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Poly [ADP-ribose] polymerase 1 (Human)	BDBM50306256 (1-(3-(pyrazin-2-yl)propanoyl)-2,3,9,9a-tetrahydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
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Poly [ADP-ribose] polymerase 2 (Human)	BDBM50306256 (1-(3-(pyrazin-2-yl)propanoyl)-2,3,9,9a-tetrahydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Protein mono-ADP-ribosyltransferase PARP3 [R100H] (Human)	BDBM50306256 (1-(3-(pyrazin-2-yl)propanoyl)-2,3,9,9a-tetrahydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Protein mono-ADP-ribosyltransferase PARP4 (Human)	BDBM50306256 (1-(3-(pyrazin-2-yl)propanoyl)-2,3,9,9a-tetrahydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
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Poly [ADP-ribose] polymerase tankyrase-1 (Human)	BDBM50306256 (1-(3-(pyrazin-2-yl)propanoyl)-2,3,9,9a-tetrahydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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