BDBM50307150 2,4-Diamino-5-methyl-6-(2',6'-dimethylphenylthio)pyrrolo[2,3-d]pyrimidine::CHEMBL596741

SMILES Cc1c(Sc2c(C)cccc2C)[nH]c2nc(N)nc(N)c12

InChI Key InChIKey=SXEALZPGUDWSCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307150   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307150(2,4-Diamino-5-methyl-6-(2',6'-dimethylphenylthio)p...)
Affinity DataIC50: 5.11nMAssay Description:Inhibition of Toxoplasma gondii DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307150(2,4-Diamino-5-methyl-6-(2',6'-dimethylphenylthio)p...)
Affinity DataIC50: 388nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed