BDBM50307871 (S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide dihydrochloride::CHEMBL597202

SMILES CC[C@@H](N)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=YHAMQFKGUUSJMU-KGLIPLIRSA-N

Data  3 KI  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50307871   

TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  140nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  180nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  180nMAssay Description:Binding affinity to thrombin (unknown origin)More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKd:  110nMAssay Description:Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetryMore data for this Ligand-Target Pair