BDBM50309154 (2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide::CHEMBL602949

SMILES O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1)C(=O)NCCc1cc(Cc2ccccc2)cs1

InChI Key InChIKey=YYPITAAWUASTAE-OPWSDZRHSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50309154   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309154((2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dih...)
Affinity DataKi:  66nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309154((2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dih...)
Affinity DataKi:  700nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309154((2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dih...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309154((2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dih...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309154((2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dih...)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309154((2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dih...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309154((2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dih...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50309154((2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dih...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed