BDBM50309295 2-(2-(bis(4-methoxyphenyl)methyl)-4-(4-fluorophenyl)thiazol-5-yl)acetic acid::CHEMBL606389

SMILES COc1ccc(cc1)C(c1nc(c(CC(O)=O)s1)-c1ccc(F)cc1)c1ccc(OC)cc1

InChI Key InChIKey=ZOTGQGLOXKIJDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309295   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309295(2-(2-(bis(4-methoxyphenyl)methyl)-4-(4-fluoropheny...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of[3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309295(2-(2-(bis(4-methoxyphenyl)methyl)-4-(4-fluoropheny...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed