BDBM50310789 3-methyl-3-phenyl-N-(pyridin-4-yl)piperidine-1-carboxamide::CHEMBL1079362

SMILES CC1(CCCN(C1)C(=O)Nc1ccncc1)c1ccccc1

InChI Key InChIKey=GHVKHDJQMCSVLZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50310789   

TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310789BDBM50310789(3-methyl-3-phenyl-N-(pyridin-4-yl)piperidine-1-car...)
Affinity DataIC50: 349nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310789BDBM50310789(3-methyl-3-phenyl-N-(pyridin-4-yl)piperidine-1-car...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310789BDBM50310789(3-methyl-3-phenyl-N-(pyridin-4-yl)piperidine-1-car...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310789BDBM50310789(3-methyl-3-phenyl-N-(pyridin-4-yl)piperidine-1-car...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310789BDBM50310789(3-methyl-3-phenyl-N-(pyridin-4-yl)piperidine-1-car...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpoxide hydrolase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50310789BDBM50310789(3-methyl-3-phenyl-N-(pyridin-4-yl)piperidine-1-car...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human microsomal epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed