BDBM50311539 2-(4-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)piperazin-1-yl)-1-(pyrrolidin-1-yl)ethanone::4-(1-benzothiophen-2-yl)-6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]pyrimidine::CHEMBL1081559

SMILES O=C(CN1CCN(CC1)c1cc(ncn1)-c1cc2ccccc2s1)N1CCCC1

InChI Key InChIKey=NDLZMZLRTHDNSQ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311539   

TargetDeoxycytidine kinase(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311539(2-(4-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)pipe...)
Affinity DataIC50:  510nMAssay Description:Inhibition of human deoxycytidine kinase by lysate filter binding assayMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311539(2-(4-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)pipe...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of dCK in human CCRF-CEM assessed as inhibition of Ara-C phosohorylationMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311539(2-(4-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)pipe...)
Affinity DataIC50:  5.10E+5nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair