BDBM50311752 CHEMBL1081870::N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-imidazo[4,5-c]pyridin-4-amine

SMILES Cc1nc2c(NCc3c(C)cccc3C)nccc2n1C

InChI Key InChIKey=RFFMAFBDIYXZRC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311752   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311752(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-imidazo[4,5...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311752(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-imidazo[4,5...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311752(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-imidazo[4,5...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311752(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-imidazo[4,5...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311752(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-imidazo[4,5...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed