BDBM50313569 (E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-methylpiperazin-1-yl)methyl)pyridin-2-yl)vinyl)nicotinonitrile::CHEMBL1084411

SMILES: CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1

InChI Key: InChIKey=RDFXBYJUHGEYHA-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50313569   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C eta type (Human)	BDBM50313569 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C epsilon type (Human)	BDBM50313569 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM50313569 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C zeta type (Human)	BDBM50313569 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50313569 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM50313569 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50313569 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C theta type (Human)	BDBM50313569 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C delta type (Human)	BDBM50313569 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
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