BDBM50313569 (E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-methylpiperazin-1-yl)methyl)pyridin-2-yl)vinyl)nicotinonitrile::CHEMBL1084411

SMILES CN1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1

InChI Key InChIKey=RDFXBYJUHGEYHA-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50313569   

TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313569((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313569((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Affinity DataIC50: 2nMAssay Description:Inhibition of PKCepsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313569((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Affinity DataIC50: 29nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313569((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Affinity DataIC50: 120nMAssay Description:Inhibition of PKCetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313569((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Affinity DataIC50: 130nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313569((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Affinity DataIC50: 540nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313569((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Affinity DataIC50: 700nMAssay Description:Inhibition of PKCbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313569((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Affinity DataIC50: 790nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50313569((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(2-(6-((4-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PKCzetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed