BDBM50313824 5-((5-methoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-phenylimidazolidine-2,4-dione::CHEMBL1087293

SMILES COc1ccc2[nH]n(CC3(NC(=O)NC3=O)c3ccccc3)c(=O)c2c1

InChI Key InChIKey=OXEVTLWXFDHNQD-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313824   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313824(5-((5-methoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-...)
Affinity DataKi:  6nMAssay Description:Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavageMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313824(5-((5-methoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-...)
Affinity DataKi:  6nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair