BDBM50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843

SMILES: CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO

InChI Key: InChIKey=MWMRJYLEVAWDDL-UHFFFAOYSA-N

Data: 19 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50314223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
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Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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Disintegrin and metalloproteinase domain-containing protein 10 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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72 kDa type IV collagenase (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
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Interstitial collagenase (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-9 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-14 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair