BDBM50314780 CHEMBL1091199::N-Cyclopropyl-3-(1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-4-methylbenzamide::N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-4-methylbenzamide

SMILES: Cc1ccc(cc1-c1cc2cnn(-c3ccc(F)cc3F)c2n(C)c1=O)C(=O)NC1CC1

InChI Key: InChIKey=XQRUWZMHPKNIDA-UHFFFAOYSA-N

Data: 2 KI  1 IC50  5 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50314780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM50314780 (N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50314780 (N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50314780 (N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50314780 (N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50314780 (N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Human)	BDBM50314780 (N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50314780 (N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314780 (N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair