BDBM50314943 1-(3,7-dimethyl-1H-indazole-5-carbonyl)-5'-isopropoxyspiro[piperidine-4,2'-pyrano[3,2-c]pyridin]-4'(3'H)-one::CHEMBL1090200

SMILES CC(C)Oc1nccc2OC3(CCN(CC3)C(=O)c3cc(C)c4[nH]nc(C)c4c3)CC(=O)c12

InChI Key InChIKey=CJQMOIBIIDORDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314943   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314943(1-(3,7-dimethyl-1H-indazole-5-carbonyl)-5'-isoprop...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314943(1-(3,7-dimethyl-1H-indazole-5-carbonyl)-5'-isoprop...)
Affinity DataIC50:  12nMAssay Description:Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed