BDBM50317865 2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole::4-(2-(4-tert-butylphenylthio)ethyl)-1H-imidazole::CHEMBL1098230

SMILES: CC(C)(C)c1ccc(SCCc2cnc[nH]2)cc1

InChI Key: InChIKey=PQPVHIHIJVIEQG-UHFFFAOYSA-N

Data: 19 KI  8 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50317865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.75	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.75	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.75	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM50317865 (2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair