BDBM50319685 1-(4-(1,4-dihydroimidazo[4,5-c]pyrazol-5-yl)-3-methylphenyl)-3-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)urea::CHEMBL1084036

SMILES Cc1cn(cn1)-c1cc(NC(=O)Nc2ccc(-c3nc4n[nH]cc4[nH]3)c(C)c2)cc(c1)C(F)(F)F

InChI Key InChIKey=DIMKSBQDWMXKAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319685   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50319685(1-(4-(1,4-dihydroimidazo[4,5-c]pyrazol-5-yl)-3-met...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human cRAF using [33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed