BDBM50322236 8-(Benzofuran-3-ylmethyl)-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one oxalate::CHEMBL1169896

SMILES CN1CN(c2ccccc2)C2(CCN(Cc3coc4ccccc34)CC2)C1=O

InChI Key InChIKey=LPZBJVXNLCRBGB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322236   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50322236(8-(Benzofuran-3-ylmethyl)-3-methyl-1-phenyl-1,3,8-...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50322236(8-(Benzofuran-3-ylmethyl)-3-methyl-1-phenyl-1,3,8-...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50322236(8-(Benzofuran-3-ylmethyl)-3-methyl-1-phenyl-1,3,8-...)
Affinity DataKi:  492nMAssay Description:Displacement of [125I]ABN from human dopamine D4 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Washington University

Curated by ChEMBL
LigandPNGBDBM50322236(8-(Benzofuran-3-ylmethyl)-3-methyl-1-phenyl-1,3,8-...)
Affinity DataKi:  708nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed