BDBM50326198 CHEMBL1242977::N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-3-(trifluoromethyl)benzamide

SMILES: CNc1nccc(n1)-c1cccnc1Oc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1C

InChI Key: InChIKey=FFNIWOOLZGAOAB-UHFFFAOYSA-N

Data: 22 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50326198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 3 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase beta-1 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.20E+3	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	503	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50326198 (N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
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